Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody is a Rabbit Polyclonal antibody against Macrophage Inflammatory Protein 1 Beta (MIP1b).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Macrophage Inflammatory Protein 1 Beta (MIP1b) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Purification | Purified by affinity chromatography using epitope-specific immunogen. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q8NHW4 |
Gene ID | 388372/9560 |
Background | Antibody anti-MIP1b |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
Related Products

Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody
MIP1b Antibody is a Rabbit Polyclonal antibody against MIP1b. Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP)-1å, MIP-1∫, MIP-2, MIP-3å, MIP-3∫, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. Research has shown that MIP-1∫ is more selective than MIP-1å, primarily attracting CD4+ T lymphocytes, with a preference for T cells of the naive phenotype. MIP-1å is a more potent lymphocyte chemoattractant than MIP-1∫ and exhibits a broader range of chemoattractant specificities. It has been suggested that CD8+ T lymphocytes are involved in the control of HIV infection in vivo by the release of HIV-suppressive factors (HIV-SF). MIP-1å has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1∫ and RANTES. Recombinant human MIP-1å acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner.
Ver Producto
Macrophage Inflammatory Protein 1 Beta (MIP1b) Antibody
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. This protein is similar to MIP1b which inhibits HIV entry by binding to the cellular receptor CCR5. The copy number of this gene varies among individuals; most individuals have 1-5 copies in the diploid genome, although rare individuals do not contain this gene at all. The human genome reference assembly contains two copies of this gene. This record represents the more centromeric gene. [provided by RefSeq].
Ver Producto
Cow Macrophage Inflammatory Protein 1 Beta (MIP1b) Protein
Recombinant MIP1b (MIP1b) is a recombinant Cow protein produced in a Prokaryotic expression system (E. coli).
Ver Producto