Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody
403€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx415279
Tested Applications
IHC, IF/ICC, FCM
Description
Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody is a Mouse Monoclonal antibody against Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) |
| Host | Mouse |
| Reactivity | Chicken |
| Assay Type | Concentration: 1.0 mg/ml |
| Recommended Dilution | Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | IHC, IF/ICC, FCM |
| Buffer | PBS. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Macrophage colony-stimulating factor 1 receptor,FMS,CSFR,FIM2,GPSC,HDLS,C-FMS,CD115,HDLS1,CSF-1R,BANDDOS,M-CSF-R,Proto-oncogene c-Fms,CSF-1 receptor |
| Background | Antibody anti-CSF1R |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
The Colony Stimulating Factor 1 Receptor (CSF1R), also known as macrophage colony-stimulating factor receptor or CD115, is a cell surface receptor that primarily regulates the survival, proliferation, and differentiation of monocytes, macrophages, and osteoclasts. CSF1R is a transmembrane protein belonging to the receptor tyrosine kinase (RTK) family and is activated by binding to its primary ligand, colony-stimulating factor 1 (CSF1), as well as the alternative ligand interleukin-34 (IL-34). This receptor is essential for various immune functions and bone metabolism, primarily because of its role in maintaining and activating macrophage populations. The CSF1R gene is located on chromosome 5 (5q32) and encodes a protein that is essential in regulating macrophage differentiation, survival, and function. CSF1R signaling influences immune response, inflammation, tissue homeostasis, and bone remodeling. Dysregulation of CSF1R or its signaling pathways has been associated with pathological conditions such as inflammatory diseases, cancer, and neurodegenerative disorders. Furthermore, mutations in CSF1R have been implicated in a group of disorders characterized by leukoencephalopathy and early-onset neurodegeneration.
Productos relacionados
Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody
CSF1R Antibody is a Rabbit Polyclonal antibody against CSF1R. The protein encoded by this gene is the receptor for colon…
Ver producto
Macrophage Colony-Stimulating Factor 1 Receptor Phospho-Tyr561 (CSF1R pY561) Antibody
Rabbit polyclonal antibody against CSFR protein. Immunogen region is Internal. Specificity is as follows for the reactiv…
Ver producto Macrophage Colony-Stimulating Factor 1 Receptor (CSF1R) Antibody
CSF1R Antibody is a Mouse Monoclonal against CSF1R.…
Ver producto