Lysyl Oxidase Homolog 1 (LOXL1) Antibody
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Description
Lysyl Oxidase Homolog 1 (LOXL1) Antibody is a Rabbit polyclonal antibody for the detection of Human Lysyl Oxidase Homolog 1 (LOXL1).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Lysyl Oxidase Homolog 1 (LOXL1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q08397 |
| Gene ID | 4016 |
| NCBI Accession | NP_005567.2 |
| Background | Antibody anti-LOXL1 |
| Status | RUO |
Descripción
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LOXL1 antibody
This gene encodes a member of the lysyl oxidase family of proteins. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyzes the first step in the formation of crosslinks in collagen and elastin. The encoded preproprotein is proteolytically processed to generate the mature enzyme. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Mutations in this gene are associated with exfoliation syndrome.
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