Lysosome Membrane Protein 2 (SCARB2) Antibody
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Description
Lysosome Membrane Protein 2 (SCARB2) Antibody is a Rabbit polyclonal antibody for the detection of Human Lysosome Membrane Protein 2 (SCARB2).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Lysosome Membrane Protein 2 (SCARB2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14108 |
| Gene ID | 950 |
| NCBI Accession | NP_001191184.1 |
| Background | Antibody anti-SCARB2 |
| Status | RUO |
Descripción
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Lysosome Membrane Protein 2 (SCARB2) Antibody
SCARB2 Antibody is a Rabbit Polyclonal antibody against SCARB2. The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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