Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) Antibody

Este producto es parte de LAMP- Lysosomal Associated Membrane Protein
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) Antibody

Pida mas información

935106861

info@markelab.com

Precio

275€ (0.1 mg)

Antibody anti-LAMP1

proveedor

Abbexa

reference

abx139700

Tested Applications

WB, IHC, IF/ICC, FCM

reactivity

Human, Monkey, Mouse

status

RUO

clonality

Monoclonal

Descripción

CD107a Antibody (Azide free) is a Mouse Monoclonal against CD107a.


Background

Lysosome-associated membrane glycoprotein 1 (LAMP1) is a transmembrane protein located on the lysosomal membrane that plays a key role in lysosome integrity, autophagy, and cellular homeostasis LAMP1 is highly expressed in cells undergoing autophagy, where it contributes to lysosomal stability and fusion with autophagosomes for the degradation of cellular waste It is involved in lysosome exocytosis, which regulates plasma membrane repair, pathogen clearance, and cellular stress responses LAMP1 also serves as a marker for lysosomal activity and has been implicated in immune responses, particularly in natural killer (NK) cell-mediated cytotoxicity Dysregulation of LAMP1 expression has been observed in neurodegenerative diseases such as Parkinson’s and Alzheimer’s, where impaired lysosomal function leads to protein aggregation and cellular toxicity Additionally, LAMP1 overexpression is associated with cancer progression and metastasis, where it facilitates cellular invasion through lysosome-mediated extracellular matrix degradation Its role in maintaining lysosomal function underscores its importance in cellular health and disease pathology

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

Human, Monkey, Mouse


immunogen target

Lysosome-Associated Membrane Glycoprotein 1 (LAMP1)


host

Mouse


conjugation

Unconjugated


tested applications

WB, IHC, IF/ICC, FCM


purity

> 95% (SDS-PAGE)


purification

Purified by Protein A affinity chromatography.


buffer

Azide free PBS, approx. pH 7.4; 0.2 µm filter sterilized.


size 1

0.1 mg


storage

Store at 2-8°C. Do not freeze.


or code

LAMP1


dry ice

No


availability

Shipped within 5-12 working days.


alias

LAMPA,CD107a,LGP120,CD107 antigen-like family member A


note

This product is for research use only.


Quizá le pueda interesar

Human LAMP1(lysosomal-associated membrane protein 1) ELISA Kit

Human LAMP1(lysosomal-associated membrane protein 1) ELISA Kit

proveedor

FineTest

reference

EH9718

reactivity

human

status

RUO

Precio a consultar

Ver más

Mouse LAMP1(Lysosomal Associated Membrane Protein 1) ELISA Kit

Mouse LAMP1(Lysosomal Associated Membrane Protein 1) ELISA Kit

proveedor

FineTest

reference

EM1182

reactivity

mouse

status

RUO

Precio a consultar

Ver más

anti- LAMP1 antibody

anti- LAMP1 antibody

proveedor

FineTest

reference

FNab04684

Tested Applications

ELISA, WB, IHC, IF

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins...

Precio a consultar

Ver más