Low Sample Volume Rat Interleukin 17A (IL17A) ELISA Kit
proveedor
Abbexareference
abx055210Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Interleukin 17A (IL17A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Interleukin 17A (IL17A) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Interleukin 17 (IL17)No significant cross-reactivity or interference between Interleukin 17A (IL17A) and analogues was observed. This kit is specifically designed for the detection of low-volume samples.
Background
The Interleukin 17 family is a group of pro-inflammatory cystine knot cytokines primarily produced by T helper 17 cells in response to stimulation with IL-23. IL17A, was previously known in rodents as CTLA8. In humans, The IL-17 family includes IL17A (sometimes referred to as "IL-17"), IL17B, IL17C, IL17D, IL17E (also known as IL-25), and IL17F. One of the most prominent roles of IL-17 is its participation in initiating and mediating proinflammatory responses. IL-17 is commonly associated with allergic reactions and can induce the production of various other cytokines (such as IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), chemokines (including IL-8, GRO-α, and MCP-1), and prostaglandins (e.g., PGE2) from different cell types, including fibroblasts, endothelial cells, epithelial cells, keratinocytes, and macrophages
Background
La familia interleucina 17 es un grupo de citocinas proinflamatorias del nudo de cistina ( 3 S_S ), producidas principalmente por células T Helper 17 en respuesta a la estimulación con IL-23. IL17A, se conocía anteriormente en roedores como CTLA8. En humanos, la familia IL-17 incluye IL17A (a veces denominada "IL-17"), IL17B, IL17C, IL17D, IL17E (también conocida como IL-25) e IL17F. Una de las funciones más destacadas de la IL-17 es su participación en el inicio y la mediación de respuestas proinflamatorias. La IL-17 se asocia comúnmente con reacciones alérgicas y puede inducir la producción de otras citoquinas (como IL-6, G-CSF, GM-CSF, IL-1β, TGF-β, TNF-α), quimiocinas (incluida IL -8, GRO-α y MCP-1) y prostaglandinas (p. ej., PGE2) de diferentes tipos de células, incluidos fibroblastos, células endoteliales, células epiteliales, queratinocitos y macrófagos.
Características del producto
category
ELISA Kits
immunogen target
Interleukin 17A (IL17A)
reactivity
Rat
test range
15.6 pg/ml - 1000 pg/ml
sensitivity
< 6.3 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
IL17,CTLA8,IL-1,ILA17,CTLA-8,IL-17A
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
IL17A
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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