Low Sample Volume Mouse Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TNFRSF1B
proveedor
Abbexareference
abx352806Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Tumor necrosis factor receptor superfamily member 1B ELISA Kit is an ELISA Kit against Tumor necrosis factor receptor superfamily member 1B.
Background
TNFRSF1B, also known as Tumor Necrosis Factor Receptor Superfamily Member 1B or TNFR2, is a cell surface receptor predominantly expressed on immune cells, including regulatory T cells (Tregs), endothelial cells, and neurons. TNFR2 is one of the two primary receptors for tumor necrosis factor-alpha (TNF-α), along with TNFR1 (TNFRSF1A). Although TNFR1 and TNFR2 both bind TNF-α, they have unique and overlapping roles within immune responses. TNFR2 primarily activates pathways that promote cell survival, tissue regeneration, and anti-inflammatory responses, differentiating it from TNFR1, which is more commonly associated with apoptosis and pro-inflammatory signaling. The TNFRSF1B gene is located on chromosome 1p36.22 and encodes a receptor of 461 amino acids. TNFR2 is a key component in regulating inflammation, modulating T cell activity, and contributing to vascular health. Its interaction with TNF-α can activate both canonical (NF-κB) and non-canonical pathways, resulting in varying cellular responses depending on the cellular environment and receptor activation context.
Características del producto
category
ELISA Kits
immunogen target
Tumor Necrosis Factor Receptor Superfamily Member 1B / CD120b (TNFRSF1B)
reactivity
Mouse
test range
7.81 pg/ml - 500 pg/ml
sensitivity
4.12 pg/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
Tumor necrosis factor receptor superfamily member 1B,p75,TBPII,TNFBR,TNFR2,CD120b,TNFR1B,TNFR80,TNF-R75,p75TNFR,TNF-R-II,Tumor necrosis factor receptor 2,p80 TNF-alpha receptor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TNFRSF1B
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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