Low Sample Volume Mouse Interferon Alpha 1 (IFNA1) ELISA Kit

Este producto es parte de IFNA1 - interferon alpha 1
Low Sample Volume Mouse Interferon Alpha 1 (IFNA1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

637€ (96 tests)

Elisa kits for IFNA1

proveedor

Abbexa

reference

abx574422

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Interferon Alpha 1 (IFNA1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Interferon Alpha 1 (IFNA1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Interferon alpha

Background

Interferon Alpha 1 (IFNA1) plays a critical role in the body's innate immune response to viral infections. It is a member of the type I interferon family and is produced by cells such as macrophages, dendritic cells, and lymphocytes in response to pathogenic challenges, including viral RNA or DNA. IFNA1 binds to the interferon-alpha/beta receptor (IFNAR) on target cells, triggering a signaling cascade that activates the JAK-STAT pathway. This leads to the transcription of numerous interferon-stimulated genes, enhancing antiviral defense mechanisms by inhibiting viral replication, promoting apoptosis of infected cells, and activating immune cells like NK cells and cytotoxic T lymphocytes. IFNA1 also plays a role in modulating the adaptive immune response by enhancing antigen presentation. Dysregulation of IFNA1 has been implicated in autoimmune conditions such as systemic lupus erythematosus (SLE), and recombinant forms of IFNA1 are used therapeutically for conditions like hepatitis B and C and certain cancers.

Características del producto

category

ELISA Kits

immunogen target

Interferon Alpha 1 (IFNA1)

reactivity

Mouse

test range

15.6 pg/ml - 1000 pg/ml

sensitivity

< 6 pg/ml

assay type

Sandwich

assay data

Quantitative

form

Lyophilized

detection method

Colorimetric

sample type

Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

size 1

96 tests

size 2

5 × 96 tests

size 3

10 × 96 tests

alias

IFL,IFN,IFNA@,IFNA13,leIF D,IFN-ALPHA,IFN-alphaD,IFN-alpha-1/13,Interferon alpha-D

storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

or code

IFNA1

dry ice

No

uniprot id

https://www.uniprot.org/uniprotkb/P01572

gene id

https://www.ncbi.nlm.nih.gov/gene/111654

note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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