Low Sample Volume Aldosterone (ALD) ELISA Kit

Este producto es parte de ALD - Aldosterone
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936€ (96 tests)

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935106861
info@markelab.com
name
Low Sample Volume Aldosterone (ALD) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx350816
tested applications
ELISA

Description

Aldosterone (ALD) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Aldosterone concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Aldosterone

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Aldosterone (ALD)
Reactivity
General
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Competitive
Test Range
24.69 pg/ml - 2000 pg/ml
Sensitivity
< 9.41 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
Aldocorten,Aldocortin
Background
Elisa kits for ALD
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Aldosterone is a steroid hormone synthesized in the zona glomerulosa of the adrenal cortex and plays a critical role in the regulation of electrolyte balance and blood pressure it acts on mineralocorticoid receptors in the kidneys to increase sodium reabsorption and potassium excretion in the distal tubules and collecting ducts this sodium retention leads to water retention contributing to blood volume and pressure maintenance aldosterone secretion is primarily regulated by the renin-angiotensin-aldosterone system (RAAS) as well as potassium levels and adrenocorticotropic hormone (ACTH) dysregulation of aldosterone can lead to conditions such as primary hyperaldosteronism (Conn's syndrome) characterized by hypertension and hypokalemia and hypoaldosteronism which can result in hyperkalemia and hypotension aldosterone measurement is crucial in diagnosing these conditions with techniques such as ELISA and CLIA commonly used to quantify its levels in plasma research into aldosterone antagonists is ongoing for the treatment of resistant hypertension and heart failure where aldosterone plays a pathological role in promoting fibrosis and vascular dysfunction

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