Low Density Lipoprotein Receptor Related Protein 6 (LRP6) Antibody
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Description
LRP6 Antibody is a Rabbit Polyclonal against LRP6.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Low Density Lipoprotein Receptor Related Protein 6 (LRP6) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/2000 - 1/10000, IHC: 1/40 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75581 |
| Gene ID | 4040 |
| Background | Antibody anti-LRP6 |
| Status | RUO |
Descripción
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Low Density Lipoprotein Receptor Related Protein 6 (LRP6) Antibody
LRP6 Antibody is a Rabbit Polyclonal antibody against LRP6. This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
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