Low Affinity Immunoglobulin Epsilon Fc Receptor (FCER2) Antibody (PE)
130€ (50 tests)
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935106861
info@markelab.com
name
Low Affinity Immunoglobulin Epsilon Fc Receptor (FCER2) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx229370
tested applications
FCM
Description
CD23 Antibody (PE) is a Mouse Monoclonal Antibody against CD23.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Low Affinity Immunoglobulin Epsilon Fc Receptor (FCER2) |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG2a Kappa |
| Size 1 | 50 tests |
| Size 2 | 100 tests |
| Size 3 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P20693 |
| Gene ID | 14128 |
| Alias | CD23,FCE2,CD23A,IGEBF,CLEC4J,FCErII,BLAST-2,Low affinity immunoglobulin epsilon Fc receptor,C-type lectin domain family 4 member J,Fc-epsilon-RII,Immunoglobulin E-binding factor,Lymphocyte IgE receptor |
| Background | Antibody anti-FCER2 |
| Status | RUO |
Descripción
FCER2, also known as CD23, is a low-affinity receptor for the Fc region of Immunoglobulin E (IgE). It is an important protein involved in the regulation of IgE-mediated immune responses and plays a key role in allergy, asthma, and immune regulation. FCER2 was first recognized for its role in B cell differentiation and later found to be expressed in several other immune cell types, including monocytes, eosinophils, dendritic cells, and macrophages. The interaction of CD23 with IgE is critical in the regulation of IgE levels and in modulating allergic responses. Unlike Fc epsilon receptor I (FCERI), which is a high-affinity receptor for IgE and is found on mast cells and basophils, CD23 has a much lower affinity for IgE and is expressed predominantly on B cells. This difference in affinity and cellular distribution allows CD23 to play a different role in immune regulation, particularly in controlling the production of IgE and mediating the interaction between IgE and antigen-presenting cells.
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