Low Affinity Immunoglobulin Epsilon Fc Receptor / CD23 (FCER2) Antibody

Este producto es parte de FCER2 - Fc epsilon receptor II
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Low Affinity Immunoglobulin Epsilon Fc Receptor / CD23 (FCER2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx145844
tested applications
ELISA, WB, IHC

Description

FCER2 Antibody is a Rabbit Polyclonal against FCER2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Low Affinity Immunoglobulin Epsilon Fc Receptor / CD23 (FCER2)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB, IHC
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
BC014108
Alias
CD23,FCE2,CD23A,IGEBF,CLEC4J,FCErII,BLAST-2,Low affinity immunoglobulin epsilon Fc receptor,C-type lectin domain family 4 member J,Fc-epsilon-RII,Immunoglobulin E-binding factor,Lymphocyte IgE receptor
Background
Antibody anti-FCER2
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. - 

Descripción

FCER2, also known as CD23, is a low-affinity receptor for the Fc region of Immunoglobulin E (IgE). It is an important protein involved in the regulation of IgE-mediated immune responses and plays a key role in allergy, asthma, and immune regulation. FCER2 was first recognized for its role in B cell differentiation and later found to be expressed in several other immune cell types, including monocytes, eosinophils, dendritic cells, and macrophages. The interaction of CD23 with IgE is critical in the regulation of IgE levels and in modulating allergic responses. Unlike Fc epsilon receptor I (FCERI), which is a high-affinity receptor for IgE and is found on mast cells and basophils, CD23 has a much lower affinity for IgE and is expressed predominantly on B cells. This difference in affinity and cellular distribution allows CD23 to play a different role in immune regulation, particularly in controlling the production of IgE and mediating the interaction between IgE and antigen-presenting cells.

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