Low Affinity Immunoglobulin Epsilon Fc Receptor / CD23 (FCER2) Antibody
169€ (20 µg)
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Name
Low Affinity Immunoglobulin Epsilon Fc Receptor / CD23 (FCER2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx109318
Tested Applications
ELISA, IHC, IF/ICC
Description
Low affinity IgE Fc receptor Antibody is a Rabbit Polyclonal antibody against Low affinity IgE Fc receptor.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Low Affinity Immunoglobulin Epsilon Fc Receptor / CD23 (FCER2) Immunogen: Recombinant human Low affinity immunoglobulin epsilon Fc receptor protein (48-321AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P06734 |
| Gene ID | 2208 |
| OMIM | 151445 |
| Alias | CD23,FCE2,CD23A,IGEBF,CLEC4J,FCErII,BLAST-2,Low affinity immunoglobulin epsilon Fc receptor,C-type lectin domain family 4 member J,Fc-epsilon-RII,Immunoglobulin E-binding factor,Lymphocyte IgE receptor |
| Background | Antibody anti-FCER2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
FCER2, also known as CD23, is a low-affinity receptor for the Fc region of Immunoglobulin E (IgE). It is an important protein involved in the regulation of IgE-mediated immune responses and plays a key role in allergy, asthma, and immune regulation. FCER2 was first recognized for its role in B cell differentiation and later found to be expressed in several other immune cell types, including monocytes, eosinophils, dendritic cells, and macrophages. The interaction of CD23 with IgE is critical in the regulation of IgE levels and in modulating allergic responses. Unlike Fc epsilon receptor I (FCERI), which is a high-affinity receptor for IgE and is found on mast cells and basophils, CD23 has a much lower affinity for IgE and is expressed predominantly on B cells. This difference in affinity and cellular distribution allows CD23 to play a different role in immune regulation, particularly in controlling the production of IgE and mediating the interaction between IgE and antigen-presenting cells.
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