Lipopolysaccharide Binding Protein (LBP) Antibody (FITC)

Este producto es parte de LBP - Lipopolysaccharide binding protein
Lipopolysaccharide Binding Protein (LBP) Antibody (FITC)

Pida mas información

935106861

info@markelab.com

Precio

162.5€ (20 µg)

Antibody anti-LBP

proveedor

Abbexa

reference

abx336397

Tested Applications

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

LBP Antibody (FITC) is a Rabbit Polyclonal against LBP.


Background

LBP is an acute-phase protein produced mainly by the liver in response to infections and inflammation It plays a crucial role in innate immunity by binding to lipopolysaccharides (LPS) from the outer membrane of Gram-negative bacteria and delivering them to CD14 and Toll-like receptor 4 (TLR4) complexes on immune cells This process triggers signaling pathways that lead to the production of pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6, initiating immune defense against bacterial infections Elevated LBP levels are observed in sepsis, systemic inflammatory response syndrome (SIRS), and chronic inflammatory diseases Dysregulation of LBP contributes to endotoxemia, where excessive immune activation results in tissue damage and organ failure It is a valuable biomarker for assessing infection severity and therapeutic outcomes in sepsis and inflammatory conditions

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Lipopolysaccharide Binding Protein (LBP)


host

Rabbit


conjugation

FITC


form

Liquid


purity

> 95%


purification

Purified by Protein G.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.


size 1

20 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.


or code

LBP


dry ice

No


availability

Shipped within 5-10 working days.


alias

BPIFD2,BPI Fold Containing Family D,LPS-Binding Protein 3


note

This product is for research use only.


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