Lipopolysaccharide Binding Protein (LBP) Antibody (FITC)
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935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-LBP
proveedor
Abbexareference
abx336397Tested Applications
reactivity
Humanstatus
RUOclonality
PolyclonalDescripción
LBP Antibody (FITC) is a Rabbit Polyclonal against LBP.
Background
LBP is an acute-phase protein produced mainly by the liver in response to infections and inflammation It plays a crucial role in innate immunity by binding to lipopolysaccharides (LPS) from the outer membrane of Gram-negative bacteria and delivering them to CD14 and Toll-like receptor 4 (TLR4) complexes on immune cells This process triggers signaling pathways that lead to the production of pro-inflammatory cytokines, including TNF-α, IL-1β, and IL-6, initiating immune defense against bacterial infections Elevated LBP levels are observed in sepsis, systemic inflammatory response syndrome (SIRS), and chronic inflammatory diseases Dysregulation of LBP contributes to endotoxemia, where excessive immune activation results in tissue damage and organ failure It is a valuable biomarker for assessing infection severity and therapeutic outcomes in sepsis and inflammatory conditions
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Lipopolysaccharide Binding Protein (LBP)
host
Rabbit
conjugation
FITC
form
Liquid
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
LBP
dry ice
No
availability
Shipped within 5-10 working days.
alias
BPIFD2,BPI Fold Containing Family D,LPS-Binding Protein 3
uniprot id
note
This product is for research use only.
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