LIMS3 Antibody (FITC)
169€ (20 µg)
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935106861
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name
LIMS3 Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx304360
Description
LIMS3 Antibody (FITC) is a Rabbit Polyclonal against LIMS3 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | LIMS3 |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P0CW19 |
| Gene ID | 100288695, 96626 |
| NCBI Accession | NP_001192217.1, NM_001205288.1 |
| Alias | LIMS3L, LIMS4, PINCH-3,LIM and senescent cell antigen-like-containing domain protein 3 |
| Background | Antibody anti-LIMS3 |
| Status | RUO |
Descripción
LIMS3 is a member of the LIM-domain-containing protein family, though it is less well-characterized compared to LIMS1 and LIMS2. It is believed to play a role in focal adhesion dynamics, cytoskeletal organization, and integrin-mediated signaling. LIMS3 contains LIM domains that facilitate protein-protein interactions, potentially linking it to actin cytoskeleton remodeling and cellular adhesion processes. Its expression appears to be tissue-specific, with enrichment in skeletal muscle, cardiac tissue, and certain epithelial cells. While the exact biological functions remain unclear, emerging evidence suggests LIMS3 may contribute to mechanical stress responses, tissue remodeling, and cell migration. Dysregulation of LIMS3 is associated with structural tissue defects and may play a role in tumor progression and metastasis. Functional studies are needed to define its precise roles in integrin signaling, cellular adhesion, and tissue-specific development.
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