Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) Antibody
357.5€ (100 µg)
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Name
Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx146215
Tested Applications
ELISA, WB, IHC
Description
LILRB4 Antibody is a Rabbit Polyclonal against LILRB4.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Leukocyte Immunoglobulin Like Receptor Subfamily B Member 4 (LILRB4) Immunogen: Recombinant fragment corresponding to 56-207 AA of human LILRB4. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC026309 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily B member 4,B4,ILT3,LIR5,CD85K,ILT-3,LIR-5,Immunoglobulin-like transcript 3,Leukocyte immunoglobulin-like receptor 5,Monocyte inhibitory receptor HM18 |
| Background | Antibody anti-LILRB4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Leukocyte Immunoglobulin-Like Receptor B4 (LILRB4), also known as CD85K, ILT3, or LIR-5, is an inhibitory receptor expressed mainly on myeloid cells, such as dendritic cells, macrophages, and monocytes. As a member of the leukocyte immunoglobulin-like receptor (LILR) family, it functions primarily to suppress immune responses, maintaining immune homeostasis and preventing overactivation. LILRB4’s immune-modulatory role is particularly crucial in preventing autoimmune reactions and regulating inflammatory responses. Its expression is primarily restricted to cells of the myeloid lineage, making it a key component in myeloid cell function. The gene encoding LILRB4 is located within a cluster of LILR genes on chromosome 19q13.4, close to other LILR genes, which are involved in immune modulation.
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