Leukocyte Immunoglobulin Like Receptor A4 (LILRA4) Antibody
442€ (200 µl)
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935106861
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name
Leukocyte Immunoglobulin Like Receptor A4 (LILRA4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432927
tested applications
P-ELISA, WB
Description
LILRA4 Antibody is a Goat Polyclonal antibody against LILRA4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Leukocyte Immunoglobulin Like Receptor A4 (LILRA4) Immunogen: abx617363 - C-Terminus: PRCSQEANSRKDN |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 23547 |
| NCBI Accession | NP_036408.3 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily A member 4,ILT7,CD85g,Immunoglobulin-like transcript 7 |
| Background | Antibody anti-LILRA4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
LILRA4 (Leukocyte Immunoglobulin-Like Receptor A4), also known as ILT7 or CD85g, is a member of the leukocyte immunoglobulin-like receptor (LILR) family, which is primarily involved in modulating immune responses. This receptor family is part of the Leukocyte Receptor Complex (LRC) on chromosome 19q13.4, where several LILR family members are located, often associated with immune regulation. LILRA4 is distinct among LILRs as it is uniquely expressed on plasmacytoid dendritic cells (pDCs), a specialized dendritic cell subset primarily responsible for antiviral responses and producing type I interferons in response to viral infection. LILRA4 plays a suppressive role on pDCs by modulating interferon production, impacting immune responses, and helping maintain immune homeostasis. The regulation of interferon responses by LILRA4 is crucial, particularly because excessive interferon production can contribute to inflammatory and autoimmune disorders
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