Leukocyte Elastase Inhibitor (SERPINB1) Antibody
Pida mas información
935106861
info@markelab.com
Precio
416€ (200 µl)
Antibody anti-SERPINB1
proveedor
Abbexareference
abx433264Tested Applications
P-ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
SERPINB1 Antibody is a Goat Polyclonal antibody against SERPINB1.
Background
SERPINB1, also known as leukocyte elastase inhibitor or monocyte neutrophil elastase inhibitor, is a member of the serine protease inhibitor (SERPIN) family. The SERPIN superfamily is one of the largest and most diverse groups of protease inhibitors, playing a crucial role in regulating various physiological processes, including inflammation, apoptosis, and immune responses. Unlike many SERPINs that inhibit proteases through a suicide substrate-like mechanism involving the formation of a covalent complex, SERPINB1 acts primarily in the intracellular environment to protect cells from protease-mediated damage. SERPINB1 is encoded by the SERPINB1 gene located on chromosome 6p25 in humans. This gene belongs to the SERPINB clade, which is a subgroup of the SERPIN family predominantly found in the cytoplasm rather than being secreted
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Leukocyte Elastase Inhibitor (SERPINB1)
host
Goat
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
P-ELISA, WB, IHC
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
recommended dilution
P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
SERPINB1
dry ice
No
availability
Shipped within 5-10 working days.
alias
EI,LEI,PI2,MNEI,PI-2,HEL57,M/NEI,ELANH2,HEL-S-27,Leukocyte elastase inhibitor,Monocyte/neutrophil elastase inhibitor,Peptidase inhibitor 2,Serpin B1
NCBI accession
NP_109591.1
note
Concentration: 0.5 mg/ml -
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