Leukocyte Elastase Inhibitor (SERPINB1) Antibody

Este producto es parte de SERPINB1 - serpin family B member 1
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416€ (200 µl)

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935106861
info@markelab.com
name
Leukocyte Elastase Inhibitor (SERPINB1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx433264
tested applications
P-ELISA, WB, IHC

Description

SERPINB1 Antibody is a Goat Polyclonal antibody against SERPINB1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Leukocyte Elastase Inhibitor (SERPINB1)
Host
Goat
Reactivity
Human
Recommended Dilution
P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA, WB, IHC
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
1992
NCBI Accession
NP_109591.1
Alias
EI,LEI,PI2,MNEI,PI-2,HEL57,M/NEI,ELANH2,HEL-S-27,Leukocyte elastase inhibitor,Monocyte/neutrophil elastase inhibitor,Peptidase inhibitor 2,Serpin B1
Background
Antibody anti-SERPINB1
Status
RUO
Note
Concentration: 0.5 mg/ml -

Descripción

SERPINB1, also known as leukocyte elastase inhibitor or monocyte neutrophil elastase inhibitor, is a member of the serine protease inhibitor (SERPIN) family. The SERPIN superfamily is one of the largest and most diverse groups of protease inhibitors, playing a crucial role in regulating various physiological processes, including inflammation, apoptosis, and immune responses. Unlike many SERPINs that inhibit proteases through a suicide substrate-like mechanism involving the formation of a covalent complex, SERPINB1 acts primarily in the intracellular environment to protect cells from protease-mediated damage. SERPINB1 is encoded by the SERPINB1 gene located on chromosome 6p25 in humans. This gene belongs to the SERPINB clade, which is a subgroup of the SERPIN family predominantly found in the cytoplasm rather than being secreted

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