L1-Cell Adhesion Molecule Phospho-Ser1181 (L1CAM pS1181) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
L1-Cell Adhesion Molecule Phospho-Ser1181 (L1CAM pS1181) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx328518
tested applications
ELISA, WB, IHC
Description
L1CAM (pS1181) Antibody is a Rabbit Polyclonal against L1CAM (pS1181).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | L1-Cell Adhesion Molecule Phospho-Ser1181 (L1CAM pS1181) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Data | Modification: Phosphorylation // Target Modification: Ser1181 |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32004 |
| Gene ID | 3897 |
| Alias | S10,HSAS,HYCX,MASA,MIC5,SPG1,CAML1,CD171,HSAS1,N-CAML1,NCAM-L1,N-CAM-L1,Neural cell adhesion molecule L1 |
| Background | Antibody anti-L1CAM |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
L1 Cell Adhesion Molecule (L1CAM) is a critical protein in the nervous system that belongs to the immunoglobulin superfamily. It plays a significant role in neural development, influencing processes such as axonal guidance, neuronal migration, and synaptic plasticity. L1CAM is predominantly expressed in the brain but is also found in other tissues, contributing to various cellular interactions. It is a transmembrane glycoprotein that mediates homophilic (L1-L1) and heterophilic (L1 with other molecules) binding, facilitating cell-cell adhesion and communication. Research into L1CAM has provided insights into its importance in both normal neural development and pathological conditions.
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