L1-Cell Adhesion Molecule (L1CAM) Antibody
273€ (100 µl)
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935106861
info@markelab.com
name
L1-Cell Adhesion Molecule (L1CAM) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx102664
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to L1-Cell Adhesion Molecule (L1CAM).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | L1-Cell Adhesion Molecule (L1CAM) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P11627 |
| Alias | S10,HSAS,HYCX,MASA,MIC5,SPG1,CAML1,CD171,HSAS1,N-CAML1,NCAM-L1,N-CAM-L1,Neural cell adhesion molecule L1 |
| Background | Antibody anti-L1CAM |
| Status | RUO |
Descripción
L1 Cell Adhesion Molecule (L1CAM) is a critical protein in the nervous system that belongs to the immunoglobulin superfamily. It plays a significant role in neural development, influencing processes such as axonal guidance, neuronal migration, and synaptic plasticity. L1CAM is predominantly expressed in the brain but is also found in other tissues, contributing to various cellular interactions. It is a transmembrane glycoprotein that mediates homophilic (L1-L1) and heterophilic (L1 with other molecules) binding, facilitating cell-cell adhesion and communication. Research into L1CAM has provided insights into its importance in both normal neural development and pathological conditions.
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