Kinase Insert Domain Receptor Phospho-Tyr1175 (KDR pY1175) Antibody is a Rabbit Polyclonal antibody for the detection of Phospho-VEGF Receptor 2-Y1175. KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas.
Primary Antibodies
Polyclonal
Human, Mouse, Rat
Kinase Insert Domain Receptor Phospho-Tyr1175 (KDR pY1175)
Rabbit
Unconjugated
Liquid
ELISA, WB, IHC
≥ 95% (SDS-PAGE)
Purified by immunogen affinity chromatography.
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
100 µg
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
KDR
No
Shipped within 5-12 working days.
This product is for research use only.
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