Killer Cell Immunoglobulin Like Receptor 2DS2 (KIR2DS2) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
KIR2DS2 Antibody is a Rabbit Polyclonal against KIR2DS2.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Killer Cell Immunoglobulin Like Receptor 2DS2 (KIR2DS2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P43631 |
| Gene ID | 100132285 |
| Alias | cl-49,nkat5,183ActI,CD158J |
| Background | Antibody anti-KIR2DS2 |
| Status | RUO |
Descripción
Related Products
Killer Cell Immunoglobulin Like Receptor 2DS2 (KIR2DS2) Antibody
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Ver Producto
Human Killer Cell Immunoglobulin Like Receptor 2DS2 (KIR2DS2) Protein
Recombinant Killer Cell Immunoglobulin Like Receptor 2DS2 (KIR2DS2) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Killer Cell Immunoglobulin Like Receptor 2DS2 (KIR2DS2) Antibody
Polyclonal Antibody to Killer Cell Immunoglobulin Like Receptor 2DS2 (KIR2DS2).
Ver Producto