Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody Pair

1014€ (5 × 96 tests)
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name
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370160
tested applications
ELISA
Description
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody Pair for use in Sandwich ELISA assay development.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Antibody Pairs  | 
| Immunogen Target | Hepatitis A Virus Cellular Receptor 1 (HAVCR1)  | 
| Reactivity | Mouse  | 
| Assay Data | Detection Antibody Biotinilated  | 
| Assay Type | Sandwich  | 
| Recommended Dilution | Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user.  | 
| Size 1 | 5 × 96 tests  | 
| Size 2 | 10 × 96 tests  | 
| Form | Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody) Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user.  | 
| Tested Applications | ELISA  | 
| Buffer | The Capture and Detection Antibody both contain 0.1% sodium azide.  | 
| Availability | Please enquire.  | 
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.  | 
| Dry Ice | No  | 
| Alias | Kidney injury molecule 1,TIM,KIM1,TIM1,CD365,HAVCR,KIM-1,TIM-1,TIMD1,TIMD-1,HAVCR-1,T-cell immunoglobulin and mucin domain-containing protein 1,T-cell immunoglobulin mucin receptor 1,T-cell membrane protein 1  | 
| Background | Antibody Pair for HAVCR1  | 
| Status | RUO  | 
| Note | This antibody pair contains ( 5 x 96 det): Detection: 50 µg Capture: 200 µg Standard: 2 µg This product is for research use only.  | 
Descripción
Hepatitis A Virus Cellular Receptor 1 (HAVCR1), also known as TIM-1 (T-cell immunoglobulin and mucin domain-containing protein 1), is a receptor protein expressed primarily on the surface of kidney epithelial cells and various immune cells. It is a member of the TIM family of proteins, which includes other receptors like TIM-3 and TIM-4. HAVCR1 plays a critical role in immune regulation, cell signaling, and disease pathogenesis, particularly within inflammatory and immune-mediated conditions. Initially identified as the receptor for hepatitis A virus (HAV), HAVCR1 has since been associated with numerous physiological and pathological processes, including immune cell activation, tissue inflammation, and the regulation of T-cell responses. HAVCR1 is implicated in immune tolerance and modulation of immune responses, making it relevant in autoimmune disorders, infections, and cancer.
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