Islet Amyloid Polypeptide (IAPP) Antibody
273€ (100 µl)
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935106861
info@markelab.com
name
Islet Amyloid Polypeptide (IAPP) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx403064
tested applications
IHC
Description
Islet Amyloid Polypeptide (IAPP) Antibody is a monoclonal antibody against Islet Amyloid Polypeptide (IAPP).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Islet Amyloid Polypeptide (IAPP) Immunogen: Recombinant Islet Amyloid Polypeptide (IAPP) Protein. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2b Kappa |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | 0.01M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Background | Antibody anti-IAPP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid(Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
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