Interleukin 3 (IL3) Antibody
273€ (100 µl)
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935106861
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name
Interleukin 3 (IL3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx131302
tested applications
IHC
Description
Interleukin 3 Antibody is a Rabbit Polyclonal against Interleukin 3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 3 (IL3) Immunogen: abx069742 - Recombinant Rat IL3 (Ile27-Cys166) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | WB (Predicted): 0.2-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | 0.01 MPBS,pH7.4,containing0.05%Proclin-300,50%glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04823 |
| Alias | IL-3,MCG, MULTI-CSF,Hematopoietic growth factor,Mast cell growth factor,MCGF,Multipotential colony-stimulating factor,P-cell-stimulating factor |
| Background | Antibody anti-IL3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Interleukin-3 (IL3) is a cytokine, a type of signaling protein involved in regulating immune and hematopoietic (blood cell formation) responses. Cytokines are crucial to the communication between cells, particularly within the immune system, helping to modulate the body's responses to pathogens, trauma, and inflammation. IL-3 is produced primarily by activated T cells, but also by other cells including mast cells, eosinophils, and monocytes, especially in response to immune challenges. Its primary function is to regulate the growth, differentiation, and survival of pluripotent hematopoietic stem cells, as well as various lineages of blood cells, making it a key player in hematopoiesis (the formation of blood cellular components). IL-3 is important not only in normal immune responses but also in pathological conditions such as allergies, autoimmune disorders, and cancers. The signaling cascade initiated by IL-3 involves several pathways, including the JAK/STAT (Janus kinase/Signal transducers and activators of transcription) and PI3K (Phosphoinositide 3-kinase)/AKT pathways, which contribute to the proliferation and survival of various cell types
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Rat Interleukin 3 (IL3) Protein
Rat IL3 Protein is a recombinant Rat protein expressed in E. coli.
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