Interleukin 3 (IL3) Antibody
507€ (0.5 mg)
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name
Interleukin 3 (IL3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx137020
Description
Interleukin 3 (IL3) Antibody is a Mouse Monoclonal antibody against Interleukin 3 (IL3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 3 (IL3) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Size 1 | 0.5 mg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | IL-3,MCG, MULTI-CSF,Hematopoietic growth factor,Mast cell growth factor,MCGF,Multipotential colony-stimulating factor,P-cell-stimulating factor |
| Background | Antibody anti-IL3 |
| Status | RUO |
Descripción
Interleukin-3 (IL3) is a cytokine, a type of signaling protein involved in regulating immune and hematopoietic (blood cell formation) responses. Cytokines are crucial to the communication between cells, particularly within the immune system, helping to modulate the body's responses to pathogens, trauma, and inflammation. IL-3 is produced primarily by activated T cells, but also by other cells including mast cells, eosinophils, and monocytes, especially in response to immune challenges. Its primary function is to regulate the growth, differentiation, and survival of pluripotent hematopoietic stem cells, as well as various lineages of blood cells, making it a key player in hematopoiesis (the formation of blood cellular components). IL-3 is important not only in normal immune responses but also in pathological conditions such as allergies, autoimmune disorders, and cancers. The signaling cascade initiated by IL-3 involves several pathways, including the JAK/STAT (Janus kinase/Signal transducers and activators of transcription) and PI3K (Phosphoinositide 3-kinase)/AKT pathways, which contribute to the proliferation and survival of various cell types
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