Interleukin 28B (IL28B) Antibody

Product specifications

Primary Antibodies

Interleukin 28B (IL28B)

Rabbit

Human

Validated in IHC-P and IHC-F. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

Purified by affinity chromatography using epitope-specific immunogen.

50 µg

100 µg

Liquid

ELISA, WB, IHC, IF/ICC

PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.

Shipped within 5-12 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

Q8IZI9

IL28B,IL28C,IL-28B,IL-28C,IFN-lambda-3,IFN-lambda-4,Cytokine Zcyto22,Interleukin-28B,Interleukin-28C

Antibody anti-IFNL3

RUO

Concentration: 1 mg/ml -

Descripción

Interferon Lambda 3 (IFNL3), also known as IL-28B, is a cytokine that belongs to the Type III interferon family, which plays a critical role in the innate immune system, particularly in antiviral defense. IFNL3, like other Type III interferons, activates signaling pathways that result in the expression of interferon-stimulated genes (ISGs), creating an antiviral state within cells. IFNL3 primarily targets epithelial cells, such as those lining the respiratory tract, gastrointestinal tract, and liver, which are common entry points for viral infections. The discovery of IFNL3 and its genetic variations has been of significant interest, especially due to its role in the treatment and clearance of hepatitis C virus (HCV) infections. Genetic polymorphisms in the IFNL3 gene are strong predictors of treatment response in HCV patients, influencing outcomes of both spontaneous viral clearance and antiviral therapy. This connection has made IFNL3 a focus of research in viral infections, where immune response to chronic infections is crucial.

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