Interleukin 23 (IL23A) Antibody (Biotin)

Este producto es parte de IL23A - interleukin 23 subunit alpha
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169€ (20 µg)

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935106861
info@markelab.com
name
Interleukin 23 (IL23A) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx317289
tested applications
ELISA

Description

IL23A Antibody (Biotin) is a Rabbit Polyclonal against IL23A conjugated to Biotin.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Interleukin 23 (IL23A)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Biotin
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9NPF7
Gene ID
51561
OMIM
605580
Alias
P19,SGRF,IL-23,L-23A,IL23P19,L-23 subunit alpha,IL-23-A,Interleukin-23 subunit p19 IL-23p19
Background
Antibody anti-IL23A
Status
RUO

Descripción

Interleukin 23A (IL23A), also referred to as IL-23, is a heterodimeric cytokine that plays a pivotal role in immune regulation, inflammation, and host defense. It is a member of the IL-12 cytokine family, which is integral to bridging the innate and adaptive immune systems. IL-23 is predominantly produced by antigen-presenting cells (such as dendritic cells and macrophages) and acts mainly on T cells, specifically promoting the differentiation, expansion, and maintenance of Th17 cells. IL-23 is essential for chronic inflammation and has been implicated in several autoimmune and inflammatory diseases, including psoriasis, rheumatoid arthritis (RA), Crohn’s disease, and multiple sclerosis (MS). Unlike its close relative IL-12, which promotes Th1 responses and interferon-γ (IFN-γ) production, IL-23 plays a critical role in the IL-23/Th17 axis, influencing the production of IL-17 and other pro-inflammatory cytokines that contribute to tissue inflammation

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