Interleukin 21 Receptor (IL21R) Antibody

169€ (20 µl)
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935106861
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name
Interleukin 21 Receptor (IL21R) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx321907
tested applications
ELISA, WB, IHC
Description
IL21R Antibody is a Rabbit Polyclonal against IL21R.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Interleukin 21 Receptor (IL21R) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/1000 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 20 µl |
Size 2 | 50 µl |
Size 3 | 100 µl |
Size 4 | 200 µl |
Size 5 | 1 ml |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9HBE5 |
Gene ID | 50615 |
OMIM | 605383 |
Alias | NILR,CD360,IMD56,IL-21 receptor,IL-21R,Novel interleukin receptor |
Background | Antibody anti-IL21R |
Status | RUO |
Descripción
Interleukin 21 receptor (IL21R) is a member of the cytokine receptor superfamily, specifically involved in immune cell communication and regulation. IL21R binds interleukin-21 (IL-21), a cytokine that plays crucial roles in immune response modulation, primarily impacting the activity of T cells, B cells, and natural killer (NK) cells. IL-21/IL21R signaling is essential for adaptive immunity, supporting the differentiation, proliferation, and functional enhancement of immune cells. This receptor is expressed on a wide range of cells within the immune system, including T and B lymphocytes, NK cells, dendritic cells, and some epithelial cells. Given its immunoregulatory functions, IL21R signaling has implications in autoimmunity, cancer immunology, and chronic inflammatory conditions.