Interleukin 21 Receptor (IL21R) Antibody
377€ (100 µg)
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Name
Interleukin 21 Receptor (IL21R) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx234252
Tested Applications
ELISA, WB, IHC, FCM
Description
IL21R Antibody is a Rabbit Polyclonal against IL21R.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 21 Receptor (IL21R) Immunogen: interleukin 21 receptor |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 68-70 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HBE5 |
| Gene ID | 50615 |
| OMIM | 605383 |
| Alias | NILR,CD360,IMD56,IL-21 receptor,IL-21R,Novel interleukin receptor |
| Background | Antibody anti-IL21R |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin 21 receptor (IL21R) is a member of the cytokine receptor superfamily, specifically involved in immune cell communication and regulation. IL21R binds interleukin-21 (IL-21), a cytokine that plays crucial roles in immune response modulation, primarily impacting the activity of T cells, B cells, and natural killer (NK) cells. IL-21/IL21R signaling is essential for adaptive immunity, supporting the differentiation, proliferation, and functional enhancement of immune cells. This receptor is expressed on a wide range of cells within the immune system, including T and B lymphocytes, NK cells, dendritic cells, and some epithelial cells. Given its immunoregulatory functions, IL21R signaling has implications in autoimmunity, cancer immunology, and chronic inflammatory conditions.
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