Interleukin 20 (IL20) Antibody

364€ (100 µg)
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935106861
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name
Interleukin 20 (IL20) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx234248
tested applications
ELISA, WB, IHC, IF/ICC
Description
IL20 Antibody is a Rabbit Polyclonal against IL20.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Interleukin 20 (IL20) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | ≥ 95% (SDS-PAGE) |
Purification | Purified by immunogen affinity chromatography. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, IF/ICC |
Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9NYY1 |
Alias | IL-20,IL10D,ZCYTO10,Cytokine Zcyto10 |
Background | Antibody anti-IL20 |
Status | RUO |
Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Interleukin 20 (IL20) is a member of the IL-10 cytokine family, which includes structurally related cytokines like IL-19, IL-22, IL-24, and IL-26. These cytokines share common biological functions in regulating immune responses, inflammation, and tissue homeostasis. IL-20, in particular, is predominantly associated with the modulation of skin, lung, and other epithelial tissues, where it exerts its effects on inflammation, tissue repair, and the innate immune response. IL-20 is produced by various cell types, including monocytes, keratinocytes, endothelial cells, and fibroblasts. Its expression is induced by pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α, particularly in tissues experiencing inflammation or injury. IL-20 acts primarily on epithelial and immune cells to regulate tissue homeostasis and inflammation, making it an important mediator in diseases like psoriasis, rheumatoid arthritis, and pulmonary inflammation.
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