Interleukin-2 Receptor Subunit Alpha (IL2RA) Antibody (FITC)

624€ (100 tests)
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935106861
info@markelab.com
name
Interleukin-2 Receptor Subunit Alpha (IL2RA) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx275087
tested applications
FCM
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin-2 Receptor Subunit Alpha (IL2RA) |
| Host | 293F cells |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | FCM: 5 µl per 106 cells in 100 µl. Optimal working dilutions could be determined by end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 Kappa |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 tests |
| Size 2 | 200 tests |
| Size 3 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at 4°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01589 |
| Gene ID | 3559 |
| Background | Antibody anti-IL2RA |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
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