Interleukin 2 Receptor Alpha (IL2RA) Antibody
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935106861
info@markelab.com
Precio
260€ (50 µl)
Antibody anti-IL2RA
proveedor
Abbexareference
abx214719Tested Applications
ELISA, WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
IL2RA Antibody is a Rabbit Polyclonal against IL2RA.
Background
Interleukin 2 receptor subunit alpha (IL2RA), also known as CD25, is a crucial component of the high-affinity interleukin-2 (IL-2) receptor complex, which is essential for regulating immune responses, particularly T-cell proliferation and survival. The IL-2 receptor plays a pivotal role in both adaptive immunity and immune tolerance, with IL2RA being one of the three subunits that form the IL-2 receptor complex. The IL-2 receptor system is critically involved in the regulation of T-cell homeostasis, immune activation, and the suppression of autoimmunity. IL2RA is primarily expressed on activated T cells, particularly regulatory T cells (Tregs), which are crucial for maintaining immune tolerance. It is also found on other immune cells, including activated B cells, dendritic cells, and natural killer (NK) cells under certain conditions. Importantly, IL2RA expression is tightly regulated, being upregulated upon T-cell activation and playing a central role in fine-tuning immune responses.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Interleukin 2 Receptor Alpha (IL2RA)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Antigen Affinity Chromatography.
recommended dilution
ELISA: 1/1000 - 1/5000, WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
size 1
50 µl
size 2
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
IL2RA
dry ice
No
availability
Shipped within 5-10 working days.
alias
p55,CD25,IL2R,IMD41,TCGFR,IDDM10,Interleukin-2 receptor subunit alpha,IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA,TAC antigen
uniprot id
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