Interleukin 19 (IL19) Antibody Pair
1326€ (5 × 96 tests)
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name
Interleukin 19 (IL19) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370579
tested applications
ELISA
Description
Interleukin 19 (IL19) Antibody Pair for use in Sandwich ELISA assay development.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Antibody Pairs |
| Immunogen Target | Interleukin 19 (IL19) |
| Reactivity | Human |
| Assay Data | Detection Antibody Biotinilated |
| Assay Type | Sandwich |
| Recommended Dilution | Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 5 × 96 tests |
| Size 2 | 10 × 96 tests |
| Form | Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody) Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user. |
| Tested Applications | ELISA |
| Buffer | The Capture and Detection Antibody both contain 0.1% sodium azide. |
| Availability | Shipped within 5-20 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | MDA1,NG.1,ZMDA1,IL-10C,Melanoma differentiation-associated protein-like protein |
| Background | Antibody Pair for IL19 |
| Status | RUO |
| Note | This antibody pair contains ( 5 x 96 det): Detection: 50 µg Capture: 200 µg Standard: 2 µg This product is for research use only. |
Descripción
Interleukin 19 (IL19) is a member of the IL-10 cytokine family, which includes other related cytokines such as IL-20, IL-22, IL-24, and IL-26. The IL-10 family plays key roles in immune regulation, inflammation, and tissue homeostasis. IL-19 was identified for its ability to influence immune responses and is involved in promoting anti-inflammatory effects and tissue repair processes, while also playing a role in the pathology of certain autoimmune and inflammatory diseases. IL-19 is primarily produced by monocytes, macrophages, keratinocytes, and other epithelial cells in response to pro-inflammatory stimuli such as lipopolysaccharides (LPS), IL-1β, and TNF-α. It is classified as a pro-inflammatory cytokine, but it exhibits immunoregulatory functions, particularly in the context of chronic inflammation. IL-19 acts through the IL-20 receptor complex, which consists of the IL-20R1 and IL-20R2 subunits, and triggers downstream signaling pathways, including the JAK-STAT pathway, to modulate the expression of various inflammatory mediators.
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