Interleukin 19 (IL-19) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Interleukin 19 (IL-19) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx234235
tested applications
ELISA, WB, IHC
Description
IL-19 Antibody is a Mouse Monoclonal against IL-19.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 19 (IL-19) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | D090 |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UHD0 |
| Alias | MDA1,NG.1,ZMDA1,IL-10C,Melanoma differentiation-associated protein-like protein |
| Background | Antibody anti-IL19 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Interleukin 19 (IL19) is a member of the IL-10 cytokine family, which includes other related cytokines such as IL-20, IL-22, IL-24, and IL-26. The IL-10 family plays key roles in immune regulation, inflammation, and tissue homeostasis. IL-19 was identified for its ability to influence immune responses and is involved in promoting anti-inflammatory effects and tissue repair processes, while also playing a role in the pathology of certain autoimmune and inflammatory diseases. IL-19 is primarily produced by monocytes, macrophages, keratinocytes, and other epithelial cells in response to pro-inflammatory stimuli such as lipopolysaccharides (LPS), IL-1β, and TNF-α. It is classified as a pro-inflammatory cytokine, but it exhibits immunoregulatory functions, particularly in the context of chronic inflammation. IL-19 acts through the IL-20 receptor complex, which consists of the IL-20R1 and IL-20R2 subunits, and triggers downstream signaling pathways, including the JAK-STAT pathway, to modulate the expression of various inflammatory mediators.
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