Interleukin 17F (IL17F) Antibody

Este producto es parte de IL17F - interleukin 17F
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364€ (100 µg)

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935106861
info@markelab.com
name
Interleukin 17F (IL17F) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx234228
tested applications
ELISA, WB

Description

IL-17F Antibody is a Rabbit Polyclonal against IL-17F.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetInterleukin 17F (IL17F)
HostRabbit
ReactivityHuman
Recommended DilutionWB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
Purity≥ 95% (SDS-PAGE)
PurificationPurified by immunogen affinity chromatography.
Size 1100 µg
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
AvailabilityShipped within 5-12 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ96PD4
AliasML1,ML-1,IL17A,CANDF6,IL-17F,Cytokine ML-1
BackgroundAntibody anti-IL17F
StatusRUO
NoteConcentration: 2 mg/ml - Validity: 12 months.

Descripción

Interleukin-17F (IL17F) is a member of the IL-17 cytokine family, which plays a pivotal role in regulating inflammatory responses and bridging the innate and adaptive immune systems. IL-17F is closely related to IL-17A, the founding member of the family, and shares functional similarities with it. Both IL-17F and IL-17A are secreted primarily by T-helper 17 (Th17) cells, a subset of CD4+ T-cells involved in immunity against extracellular pathogens, especially fungi and bacteria. In addition to Th17 cells, IL-17F can also be produced by other cell types such as natural killer (NK) cells, innate lymphoid cells (ILCs), and neutrophils. IL-17F is implicated in several immune-mediated processes, including the promotion of inflammation in tissues. It is primarily associated with the pathogenesis of autoimmune diseases such as psoriasis, asthma, and inflammatory bowel disease (IBD).

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