Interleukin 17D (IL17D) Antibody
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935106861
info@markelab.com
Precio
250€ (80 µl)
Antibody anti-IL17D
proveedor
Abbexareference
abx028222Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
Background
Interleukin 17D (IL17D) is a member of the IL-17 cytokine family, which plays a crucial role in modulating the immune response, particularly in inflammation and host defense. The IL-17 family consists of six cytokines (IL-17A through IL-17F), all of which are involved in regulating immune responses, especially those associated with infection, autoimmunity, and tissue inflammation. IL-17D is one of the less well-characterized members of this family, but it is known to have distinct roles in the regulation of innate immunity, particularly in the induction of inflammatory cytokines in various tissues. Unlike the more widely studied IL-17A and IL-17F, which are produced by Th17 cells and have well-established roles in inflammatory diseases, the function of IL-17D has only recently come to light. It is expressed in a variety of non-hematopoietic cells, including fibroblasts, endothelial cells, and smooth muscle cells, where it acts to modulate immune responses by inducing the production of inflammatory cytokines and recruiting immune cells
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Interleukin 17D (IL17D)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified through a protein A column, followed by peptide affinity purification.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
IL17D
dry ice
No
availability
Shipped within 5-10 working days.
alias
IL-17D,Interleukin-27,IL27,IL-27
uniprot id
note
This product is for research use only.
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