Interleukin 17D (IL17D) Antibody

Este producto es parte de IL17D - interleukin 17D
Interleukin 17D (IL17D) Antibody

Pida mas información

935106861

info@markelab.com

Precio

250€ (80 µl)

Antibody anti-IL17D

proveedor

Abbexa

reference

abx028222

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.


Background

Interleukin 17D (IL17D) is a member of the IL-17 cytokine family, which plays a crucial role in modulating the immune response, particularly in inflammation and host defense. The IL-17 family consists of six cytokines (IL-17A through IL-17F), all of which are involved in regulating immune responses, especially those associated with infection, autoimmunity, and tissue inflammation. IL-17D is one of the less well-characterized members of this family, but it is known to have distinct roles in the regulation of innate immunity, particularly in the induction of inflammatory cytokines in various tissues. Unlike the more widely studied IL-17A and IL-17F, which are produced by Th17 cells and have well-established roles in inflammatory diseases, the function of IL-17D has only recently come to light. It is expressed in a variety of non-hematopoietic cells, including fibroblasts, endothelial cells, and smooth muscle cells, where it acts to modulate immune responses by inducing the production of inflammatory cytokines and recruiting immune cells

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Interleukin 17D (IL17D)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB


purification

Purified through a protein A column, followed by peptide affinity purification.


buffer

PBS containing 0.09% sodium azide.


size 1

80 µl


size 2

400 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

IL17D


dry ice

No


availability

Shipped within 5-10 working days.


alias

IL-17D,Interleukin-27,IL27,IL-27


note

This product is for research use only.


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