Interleukin 17C (IL17C) Antibody
260€ (50 µl)
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935106861
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name
Interleukin 17C (IL17C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx211282
tested applications
ELISA, WB, IHC
Description
IL17C Antibody is a Rabbit Polyclonal against IL17C.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 17C (IL17C) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P0M4 |
| Gene ID | 27189 |
| Alias | CX2,IL-17C,Cytokine CX2 |
| Background | Antibody anti-IL17C |
| Status | RUO |
Descripción
Interleukin 17C (IL17C) is a member of the IL-17 cytokine family, which is heavily involved in immune responses, particularly in inflammatory and autoimmune processes. The IL-17 family includes six members: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (IL-25), and IL-17F, all of which contribute in varying ways to host defense, primarily by inducing inflammatory responses. IL-17C plays a distinct role in mucosal immunity, primarily by acting as a mediator of the host defense against bacterial pathogens, particularly at epithelial barriers. IL-17C has drawn interest because of its autocrine and paracrine signaling capabilities, meaning that it can act both on the cells that produce it (autocrine signaling) and on neighboring cells (paracrine signaling). In contrast to IL-17A and IL-17F, which are secreted by Th17 cells, IL-17C is predominantly produced by epithelial cells. Its role in enhancing the immune response to infection makes it critical for barrier defense in tissues like the skin, lungs, intestines, and other mucosal surfaces
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