Interleukin 17C (IL17C) Antibody

Este producto es parte de IL17C - interleukin 17C
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286€ (100 µl)

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935106861
info@markelab.com
name
Interleukin 17C (IL17C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx101515
tested applications
WB, IHC, IF/ICC

Description

Polyclonal Antibody to Interleukin 17C (IL17C).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetInterleukin 17C (IL17C)
HostRabbit
ReactivityMouse
Recommended DilutionWB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
PurificationPurified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1100 µl
Size 2200 µl
Size 31 ml
FormLiquid
Tested ApplicationsWB, IHC, IF/ICC
Buffer0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
AvailabilityShipped within 5-7 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ8K4C5
AliasCX2,IL-17C,Cytokine CX2
BackgroundAntibody anti-IL17C
StatusRUO

Descripción

Interleukin 17C (IL17C) is a member of the IL-17 cytokine family, which is heavily involved in immune responses, particularly in inflammatory and autoimmune processes. The IL-17 family includes six members: IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (IL-25), and IL-17F, all of which contribute in varying ways to host defense, primarily by inducing inflammatory responses. IL-17C plays a distinct role in mucosal immunity, primarily by acting as a mediator of the host defense against bacterial pathogens, particularly at epithelial barriers. IL-17C has drawn interest because of its autocrine and paracrine signaling capabilities, meaning that it can act both on the cells that produce it (autocrine signaling) and on neighboring cells (paracrine signaling). In contrast to IL-17A and IL-17F, which are secreted by Th17 cells, IL-17C is predominantly produced by epithelial cells. Its role in enhancing the immune response to infection makes it critical for barrier defense in tissues like the skin, lungs, intestines, and other mucosal surfaces

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