Interleukin 17A (IL17A) Antibody (FITC)

Este producto es parte de IL17A - Interleukin 17A
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104€ (50 tests)

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935106861
info@markelab.com
name
Interleukin 17A (IL17A) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx229441
tested applications
FCM

Description

Interleukin 17A (IL17A) Antibody (FITC) is a Mouse Monoclonal Antibody against Interleukin 17A (IL17A).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Interleukin 17A (IL17A)
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
FITC
Isotype
IgG1 Kappa
Size 1
50 tests
Size 2
100 tests
Size 3
200 tests
Tested Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze.
Dry Ice
No
UniProt ID
Q62386
Gene ID
16171
Alias
IL17,CTLA8,IL-1,ILA17,CTLA-8,IL-17A
Background
Antibody anti-IL17A
Status
RUO

Descripción

IL17A is a pro-inflammatory cytokine produced primarily by T-helper 17 (Th17) cells and other immune cells in response to infection and tissue damage IL17A plays a central role in innate and adaptive immunity by stimulating the production of chemokines, cytokines, and antimicrobial peptides that recruit neutrophils and enhance host defense against bacterial and fungal infections Dysregulated IL17A production is associated with autoimmune diseases such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease, where it contributes to chronic inflammation and tissue damage IL17A also plays a role in cancer, where it can promote tumor growth and metastasis by inducing angiogenesis, immune suppression, and chronic inflammation IL17A-targeted therapies, including monoclonal antibodies such as secukinumab, have been developed to treat autoimmune and inflammatory conditions by neutralizing IL17A activity and reducing inflammation

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