Interleukin 17A (IL17A) Antibody (Biotin)

Este producto es parte de IL17A - Interleukin 17A
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650€ (50 µg)

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935106861
info@markelab.com
name
Interleukin 17A (IL17A) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx412344
tested applications
ELISA

Description

Interleukin 17A (IL17A) Antibody (Biotin) is a Rabbit Polyclonal antibody against Interleukin 17A (IL17A).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetInterleukin 17A (IL17A)
HostRabbit
ReactivityPig
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationBiotin
IsotypeIgG
PurificationPurified
Size 150 µg
FormLiquid
Tested ApplicationsELISA
BufferPBS. Contains sodium azide.
AvailabilityShipped within 3-7 working days.
StorageAliquot and store at 2°C to 8°C upon receipt.
Dry IceNo
UniProt IDQ60I29
AliasIL17,CTLA8,IL-1,ILA17,CTLA-8,IL-17A
BackgroundAntibody anti-IL17A
StatusRUO
NoteConcentration: 1.0 mg/ml -

Descripción

IL17A is a pro-inflammatory cytokine produced primarily by T-helper 17 (Th17) cells and other immune cells in response to infection and tissue damage IL17A plays a central role in innate and adaptive immunity by stimulating the production of chemokines, cytokines, and antimicrobial peptides that recruit neutrophils and enhance host defense against bacterial and fungal infections Dysregulated IL17A production is associated with autoimmune diseases such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease, where it contributes to chronic inflammation and tissue damage IL17A also plays a role in cancer, where it can promote tumor growth and metastasis by inducing angiogenesis, immune suppression, and chronic inflammation IL17A-targeted therapies, including monoclonal antibodies such as secukinumab, have been developed to treat autoimmune and inflammatory conditions by neutralizing IL17A activity and reducing inflammation

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