Interleukin 17 Receptor A (IL17RA) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Interleukin 17 Receptor A (IL17RA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx325591
tested applications
ELISA, WB
Description
IL17RA Antibody is a Rabbit Polyclonal against IL17RA.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Interleukin 17 Receptor A (IL17RA) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/40000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96F46 |
| Gene ID | 23765 |
| Alias | IL-17 receptor A,CD217,IL17R,IMD51,CANDF5,CDw217,IL-17RA |
| Background | Antibody anti-IL17RA |
| Status | RUO |
Descripción
Interleukin-17 receptor A (IL17RA) is a protein critical for immune responses, especially in mediating host defense against extracellular pathogens and in inflammatory processes. IL17RA is the primary receptor for the IL-17 family of cytokines, a group known to play key roles in driving immune responses by recruiting neutrophils and promoting inflammation. Among the IL-17 family, IL-17A and IL-17F are particularly significant in immune signaling via IL17RA. IL-17 cytokines and their receptors have been extensively studied for their involvement in autoimmune diseases, inflammatory conditions, and some cancers, where dysregulated IL-17 signaling leads to excessive or persistent inflammation. IL17RA, as a receptor, is broadly expressed across various cell types, including epithelial cells, fibroblasts, macrophages, and dendritic cells. This widespread expression pattern reflects the receptor’s role in both the immune and non-immune cells, enabling it to participate in the body's initial responses to infection and inflammation.
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