Interleukin 17A (IL17A) Antibody (Biotin)

Este producto es parte de IL17A - Interleukin 17A
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403€ (200 µl)

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935106861
info@markelab.com
name
Interleukin 17A (IL17A) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx273050
tested applications
WB, IHC, IF/ICC

Description

Interleukin 17A (IL17A) Antibody (Biotin) is a Guinea pig Polyclonal antibody conjugated to Biotin against Interleukin 17A (IL17A).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Interleukin 17A (IL17A)
Host
Guinea pig
Reactivity
Rabbit
Recommended Dilution
WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Biotin
Isotype
IgG
Purification
Purified by antigen-specific affinity chromatography.
Size 1
200 µl
Size 2
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
IL17,CTLA8,IL-1,ILA17,CTLA-8,IL-17A
Background
Antibody anti-IL17A
Status
RUO

Descripción

IL17A is a pro-inflammatory cytokine produced primarily by T-helper 17 (Th17) cells and other immune cells in response to infection and tissue damage IL17A plays a central role in innate and adaptive immunity by stimulating the production of chemokines, cytokines, and antimicrobial peptides that recruit neutrophils and enhance host defense against bacterial and fungal infections Dysregulated IL17A production is associated with autoimmune diseases such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease, where it contributes to chronic inflammation and tissue damage IL17A also plays a role in cancer, where it can promote tumor growth and metastasis by inducing angiogenesis, immune suppression, and chronic inflammation IL17A-targeted therapies, including monoclonal antibodies such as secukinumab, have been developed to treat autoimmune and inflammatory conditions by neutralizing IL17A activity and reducing inflammation
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