Interleukin 17A (IL17A) Antibody
Pida mas información
935106861
info@markelab.com
Precio
812.5€ (1 ml)
Antibody anti-IL17A
proveedor
Abbexareference
abx173099Tested Applications
WB, IHC, IF/ICCreactivity
Dogstatus
RUOclonality
MonoclonalDescripción
This product is currently in development. The lead time for this product may be several months. Please contact us at info@markelab.com for an updated lead time before purchasing this product. Interleukin 17A (IL17A) Antibody is a Mouse Monoclonal antibody against Interleukin 17A (IL17A).
Background
IL17A is a pro-inflammatory cytokine produced primarily by T-helper 17 (Th17) cells and other immune cells in response to infection and tissue damage IL17A plays a central role in innate and adaptive immunity by stimulating the production of chemokines, cytokines, and antimicrobial peptides that recruit neutrophils and enhance host defense against bacterial and fungal infections Dysregulated IL17A production is associated with autoimmune diseases such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease, where it contributes to chronic inflammation and tissue damage IL17A also plays a role in cancer, where it can promote tumor growth and metastasis by inducing angiogenesis, immune suppression, and chronic inflammation IL17A-targeted therapies, including monoclonal antibodies such as secukinumab, have been developed to treat autoimmune and inflammatory conditions by neutralizing IL17A activity and reducing inflammation
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Dog
immunogen target
Interleukin 17A (IL17A)
host
Mouse
conjugation
Unconjugated
form
Liquid
tested applications
WB, IHC, IF/ICC
purification
Purified by Protein A and Protein G affinity chromatography.
buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
size 1
1 ml
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
IL17A
dry ice
No
availability
Please enquire.
alias
IL17,CTLA8,IL-1,ILA17,CTLA-8,IL-17A
note
This product is for research use only.
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