Interleukin 17A (IL17A) Antibody

Este producto es parte de IL17A - Interleukin 17A
Interleukin 17A (IL17A) Antibody

Pida mas información

935106861

info@markelab.com

Precio

812.5€ (1 ml)

Antibody anti-IL17A

proveedor

Abbexa

reference

abx173099

Tested Applications

WB, IHC, IF/ICC

reactivity

Dog

status

RUO

clonality

Monoclonal

Descripción

This product is currently in development. The lead time for this product may be several months. Please contact us at info@markelab.com for an updated lead time before purchasing this product. Interleukin 17A (IL17A) Antibody is a Mouse Monoclonal antibody against Interleukin 17A (IL17A).


Background

IL17A is a pro-inflammatory cytokine produced primarily by T-helper 17 (Th17) cells and other immune cells in response to infection and tissue damage IL17A plays a central role in innate and adaptive immunity by stimulating the production of chemokines, cytokines, and antimicrobial peptides that recruit neutrophils and enhance host defense against bacterial and fungal infections Dysregulated IL17A production is associated with autoimmune diseases such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease, where it contributes to chronic inflammation and tissue damage IL17A also plays a role in cancer, where it can promote tumor growth and metastasis by inducing angiogenesis, immune suppression, and chronic inflammation IL17A-targeted therapies, including monoclonal antibodies such as secukinumab, have been developed to treat autoimmune and inflammatory conditions by neutralizing IL17A activity and reducing inflammation

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

Dog


immunogen target

Interleukin 17A (IL17A)


host

Mouse


conjugation

Unconjugated


form

Liquid


tested applications

WB, IHC, IF/ICC


purification

Purified by Protein A and Protein G affinity chromatography.


buffer

0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.


size 1

1 ml


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

IL17A


dry ice

No


availability

Please enquire.


alias

IL17,CTLA8,IL-1,ILA17,CTLA-8,IL-17A


note

This product is for research use only.


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