Interleukin 13 Receptor Alpha 1 Phospho-Tyr405 (IL13RA1 pY405) Antibody
221€ (50 µg)
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Name
Interleukin 13 Receptor Alpha 1 Phospho-Tyr405 (IL13RA1 pY405) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx328053
Tested Applications
ELISA, WB, IF/ICC
Description
Interleukin 13 Receptor Alpha 1 Phospho-Tyr405 (IL13RA1 pY405) Antibody is a Rabbit Polyclonal against IL13RA1 (pY405).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 13 Receptor Alpha 1 Phospho-Tyr405 (IL13RA1 pY405) Immunogen: Synthesized peptide derived from human IL-13Rα1 around the phosphorylation site of Y405. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P78552 |
| Gene ID | 3597 |
| Alias | IL-13 receptor subunit alpha-1,NR4,CT19,CD213A1,IL-13Ra,IL-13R subunit alpha-1 |
| Background | Antibody anti-IL13Ra1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin-13 receptor subunit alpha-1 (IL13RA1) is a protein that serves as a primary component of the interleukin-13 receptor (IL-13R) complex, a receptor essential for immune regulation and inflammatory responses. IL13RA1, encoded by the IL13RA1 gene, is a type I cytokine receptor that primarily binds to the cytokine interleukin-13 (IL-13), a cytokine associated with type 2 helper T cell (Th2) immune responses. IL13RA1 also participates in binding interleukin-4 (IL-4), a cytokine closely related to IL-13 in function and structure, by forming a complex with IL-4 receptor alpha (IL4RA). IL13RA1’s function in the immune system is particularly significant in responses to allergens, where it helps mediate the characteristic responses associated with allergic asthma, atopic dermatitis, and allergic rhinitis. Beyond allergy and inflammation, IL13RA1’s signaling pathways are implicated in fibrotic diseases and certain cancers, as IL-13 and IL-4 promote tissue remodeling, fibrosis, and immune modulation.
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