Interleukin 12A (IL12A) Antibody
273€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Interleukin 12A (IL12A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx132018
Tested Applications
WB
Description
Interleukin 12A Antibody is a Mouse Monoclonal against Interleukin 12A.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 12A (IL12A) Immunogen: Arg23-Ser219 |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-5 µg/ml, IHC (Predicted): 5-30 µg/ml, IF/ICC (Predicted): 5-30 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2b Kappa |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P29459 |
| Alias | P35,CLMF,NFSK,NKSF1,IL-12A,Cytotoxic lymphocyte maturation factor 35 kDa subunit,CLMF p35,IL-12 subunit p35,NK cell stimulatory factor chain 1 |
| Background | Antibody anti-IL12A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Interleukin 12A (IL12A) is a subunit of the heterodimeric cytokine interleukin-12, which plays a pivotal role in the immune system by bridging innate and adaptive immunity. IL12A, also known as IL-12p35, pairs with the IL12B subunit (IL-12p40) to form the active cytokine IL-12, which is essential for inducing T-helper 1 (Th1) immune responses. IL12A is produced by activated antigen-presenting cells, such as macrophages and dendritic cells, in response to infections or immune challenges. It functions by stimulating natural killer (NK) cells and CD4+ T-cells to produce interferon-gamma (IFN-γ), a cytokine critical for pathogen clearance and enhancing cytotoxic activities. Dysregulation of IL12A expression has been associated with autoimmune diseases, chronic inflammation, and cancer. Therapeutic strategies targeting IL12A, including IL-12 inhibitors or engineered cytokines, are being explored for managing these conditions and for enhancing anti-tumor immune responses.
Productos relacionados
Low Sample Volume Mouse Interleukin 12 (IL12) ELISA Kit
Mouse IL-12 ELISA kit is an ELISA kit against Mouse IL-12.…
Ver producto Low Sample Volume Human Interleukin 12 (IL12) ELISA Kit
Low Sample Volume Human Interleukin 12 (IL12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Hum…
Ver producto
Human Interleukin 12A (IL12A) Protein
Human Interleukin 12A (IL12A) is a recombinant Human protein expressed in E. coli.…
Ver producto