Interleukin 11 (IL11) Antibody
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Pida mas información
935106861
info@markelab.com
Precio
754€ (1 ml)
Antibody anti-IL11
proveedor
Abbexareference
abx177083Tested Applications
WB, IHC, IF/ICCreactivity
Ratstatus
RUOclonality
PolyclonalDescripción
This product is currently in development. The lead time for this product may be several months. Please contact us at
Background
Interleukin-11 (IL11) is a member of the IL-6-type cytokine family, which plays crucial roles in regulating immune responses, inflammation, and hematopoiesis. IL-11 was first identified for its role in promoting the proliferation of hematopoietic stem cells and megakaryocytes, which are essential for platelet production. Since then, IL-11 has been implicated in various biological processes, including tissue regeneration, bone remodeling, and immune system regulation. IL-11 signals through its specific receptor complex, initiating various downstream signaling cascades, primarily through the JAK/STAT pathway. IL-11 is mainly secreted by stromal cells, fibroblasts, and epithelial cells in response to various stimuli, including inflammatory signals. While initially considered a supportive cytokine in hematopoiesis, more recent studies have shown that IL-11 plays a significant role in tissue fibrosis, chronic inflammation, and even cancer progression
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Rat
immunogen target
Interleukin 11 (IL11)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
WB, IHC, IF/ICC
purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
recommended dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
size 1
1 ml
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
IL11
dry ice
No
availability
Please enquire.
alias
AGIF,IL-11,Adipogenesis inhibitory factor,Oprelvekin
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