Interleukin 11 (IL11) Antibody
260€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Interleukin 11 (IL11) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx101177
tested applications
WB
Description
Polyclonal Antibody to Interleukin 11 (IL11).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 11 (IL11) Immunogen: abx067430 - Recombinant IL11 (Pro22-Leu199) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20809 |
| Alias | AGIF,IL-11,Adipogenesis inhibitory factor,Oprelvekin |
| Background | Antibody anti-IL11 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Interleukin-11 (IL11) is a member of the IL-6-type cytokine family, which plays crucial roles in regulating immune responses, inflammation, and hematopoiesis. IL-11 was first identified for its role in promoting the proliferation of hematopoietic stem cells and megakaryocytes, which are essential for platelet production. Since then, IL-11 has been implicated in various biological processes, including tissue regeneration, bone remodeling, and immune system regulation. IL-11 signals through its specific receptor complex, initiating various downstream signaling cascades, primarily through the JAK/STAT pathway. IL-11 is mainly secreted by stromal cells, fibroblasts, and epithelial cells in response to various stimuli, including inflammatory signals. While initially considered a supportive cytokine in hematopoiesis, more recent studies have shown that IL-11 plays a significant role in tissue fibrosis, chronic inflammation, and even cancer progression
Related Products
Human Interleukin 11 (IL11) Protein
Human Interleukin 11 (IL11) is a recombinant Human protein expressed in E. coli.
Ver Producto