Interleukin 11 (IL11) Antibody

Product specifications

Primary Antibodies

Interleukin 11 (IL11)

Rabbit

Human, Mouse, Rat

ELISA: 1 µg/ml, WB: 1/1000 - 1/5000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

IgG

Purified by affinity chromatography.

20 µl

100 µl

2 × 100 µl

Liquid

ELISA, WB, IF/ICC

PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.

Shipped within 5-10 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

P20809

3589

NP_000632.1

AGIF,IL-11,Adipogenesis inhibitory factor,Oprelvekin

Antibody anti-IL11

RUO

Concentration: > 0.2 mg/ml -

Descripción

Interleukin-11 (IL11) is a member of the IL-6-type cytokine family, which plays crucial roles in regulating immune responses, inflammation, and hematopoiesis. IL-11 was first identified for its role in promoting the proliferation of hematopoietic stem cells and megakaryocytes, which are essential for platelet production. Since then, IL-11 has been implicated in various biological processes, including tissue regeneration, bone remodeling, and immune system regulation. IL-11 signals through its specific receptor complex, initiating various downstream signaling cascades, primarily through the JAK/STAT pathway. IL-11 is mainly secreted by stromal cells, fibroblasts, and epithelial cells in response to various stimuli, including inflammatory signals. While initially considered a supportive cytokine in hematopoiesis, more recent studies have shown that IL-11 plays a significant role in tissue fibrosis, chronic inflammation, and even cancer progression

Related Products

Human IL-11 (Interleukin 11) ELISA Kit

Ver Producto

Mouse Il-11 (Interleukin-11) ELISA Kit

Ver Producto

Porcine IL-11 (Interleukin-11) ELISA Kit

Ver Producto