Interferon Lambda-3 (IFNL3) Antibody

Este producto es parte de IFNL3 - interferon lambda 3
Product Graph
260€ (50 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Interferon Lambda-3 (IFNL3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx339614
tested applications
ELISA, WB

Description

IFNL3 Antibody is a Rabbit Polyclonal against IFNL3.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Interferon Lambda-3 (IFNL3)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/1000 - 1/2000, WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
50 µl
Size 2
100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q8IZI9
Gene ID
282617
Alias
IL28B,IL28C,IL-28B,IL-28C,IFN-lambda-3,IFN-lambda-4,Cytokine Zcyto22,Interleukin-28B,Interleukin-28C
Background
Antibody anti-IFNL3
Status
RUO

Descripción

Interferon Lambda 3 (IFNL3), also known as IL-28B, is a cytokine that belongs to the Type III interferon family, which plays a critical role in the innate immune system, particularly in antiviral defense. IFNL3, like other Type III interferons, activates signaling pathways that result in the expression of interferon-stimulated genes (ISGs), creating an antiviral state within cells. IFNL3 primarily targets epithelial cells, such as those lining the respiratory tract, gastrointestinal tract, and liver, which are common entry points for viral infections. The discovery of IFNL3 and its genetic variations has been of significant interest, especially due to its role in the treatment and clearance of hepatitis C virus (HCV) infections. Genetic polymorphisms in the IFNL3 gene are strong predictors of treatment response in HCV patients, influencing outcomes of both spontaneous viral clearance and antiviral therapy. This connection has made IFNL3 a focus of research in viral infections, where immune response to chronic infections is crucial.

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